Enabling stem
cell therapy with bioengineered tissues

Enabling stem
cell therapy with bioengineered tissues

A preclinical tissue therapeutics company driving a paradigm shift in modern medicine.

TISSUE THERAPEUTICS

Human cells have immense potential to restore and regenerate lost cell and organ function — but cells alone aren't enough.

Tissue Therapeutics

Our VivoSet™ technology enables the creation of fully vascularized therapeutic tissues, providing a thriving cellular microenvironment to restore lost cell and organ function, permanently.

Perfusible Microvasculature

Engineered with microvascular networks, our tissues ensure rapid engraftment and anastomosis with host vasculature. This enables efficient exchange of nutrients and therapeutic products.

Cell-synthesized Extracellular Matrix (ECM)

Our tissues are entirely cell-synthesized, with no artificial materials, eliminating the risk of fibrotic responses. This ensures better integration with the host environment, allowing cells to thrive and supporting long-term functionality.

Embedded Therapeutic Cells

VivoSet™ tissues are loaded with function-specific therapeutic cells, supported by a holistic multicellular architecture. This integrated approach effectively restores complex cellular and organ functions.

3
2
Tap to Learn More
1
Tap to Learn More
3
2
1
pROBLEM

Type I Diabetes

Glucose levels fluctuate throughout the day
Blood glucose levels, mmol/l

Type 1 Diabetes patients suffer debilitating side effects if their blood glucose falls out of the normal range for extended
periods. Tissue therapeutics can replace lost or damaged insulin-producing functions, freeing patients of the burden to actively manage their blood glucose levels

Source: Diabetes UK

Advanced liver diseases

Change in mortality rates from chronic disease
Per 100, 000 population (USA), normalized to the year 2000

Life expectancy for those suffering from chronic liver diseases & cirrhosis has not improved over the past two decades. We need new therapeutic approaches that can improve outcomes for patients with advanced liver disease

Sources: IHME, Global Burden of Disease (2019), WHO Mortality Database (2022)

Heart disease

After a heart attack, some of the heart’s muscles can be left damaged beyond repair, leaving patients at high risk of mortality or developing heart disease. Tissue therapeutics has the potential to replace damaged heart muscle, improving quality of life for people who are starting their journey of recovery after a debilitating heart attack

Source: Jenča et al. 2020, Ye et al. 2020

Chronic diseases with no solutions

Modern medicine has tackled formidable challenges, achieving breakthroughs in treating cancers and cardiovascular diseases. Yet, for certain conditions, effective solutions remain elusive — traditional drugs and cell therapies fall short, unable to address complex disease mechanisms and fully restore lost functions.

Technology should enable biology, not replace it.